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Steady-state plasma tirzepatide concentrations were achieved following 4 weeks of once weekly administration

In the body, through flavokinase and FAD synthetase, riboflavin is converted to its active forms, flavin mononucleotide (FMN) first, and then flavin adenine dinucleotide (FAD), which are essential for the synthesis of various compounds, including niacin, folic acid, vitamin B6, and heme proteins (43)